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feat: Add cigar(::Haplotype) function
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2 changed files with 30 additions and 1 deletions
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@ -221,6 +221,35 @@ function reconstruct(h::Haplotype)
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return seq
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return seq
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end
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end
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"""
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cigar(hap::Haplotype{S,T}) where {S,T}
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Constructs a CIGAR string representing the alignment of the sequence of `hap` to its
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reference.
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"""
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function BioAlignments.cigar(hap::Haplotype{S,T}) where {S,T}
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cigar_string = String[]
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mismatch_vars = filter(var -> !isa(mutation(var), Substitution), variations(hap))
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length(mismatch_vars) > 0 || return "$(length(reference(hap)))M"
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lastvar = first(mismatch_vars)
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leftposition(lastvar) > 1 && push!(cigar_string, "$(leftposition(lastvar))M")
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for var in mismatch_vars
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push!(cigar_string, _cigar_between(lastvar, var))
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push!(cigar_string, _cigar(var))
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lastvar = var
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end #for
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remaining_bases = length(reference(hap)) - rightposition(lastvar)
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remaining_bases > 0 && push!(cigar_string, "$(remaining_bases)M")
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return join(cigar_string, "")
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end
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"""
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"""
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translate(hap::Haplotype{S,T}, aln::PairwiseAlignment{S,S}) where {S,T}
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translate(hap::Haplotype{S,T}, aln::PairwiseAlignment{S,S}) where {S,T}
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@ -20,7 +20,7 @@ TODO now:
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* Add tests
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* Add tests
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"""
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"""
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using BioAlignments: BioAlignments, PairwiseAlignment, OP_SOFT_CLIP, sequence
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using BioAlignments: BioAlignments, PairwiseAlignment, OP_SOFT_CLIP, cigar, sequence
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using BioGenerics: BioGenerics, leftposition, rightposition
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using BioGenerics: BioGenerics, leftposition, rightposition
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using BioSequences: BioSequences, BioSequence, NucleotideSeq, LongSequence, isgap
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using BioSequences: BioSequences, BioSequence, NucleotideSeq, LongSequence, isgap
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using BioSymbols: BioSymbol
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using BioSymbols: BioSymbol
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