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nextflow run /path/to/workflows/nf-core-rnaseq-3.0/workflow -profile mycluster
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```
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If you prefer, you can download these config profiles yourself and customise the `--custom_config_base` / `params.custom_config_base` parameter in each pipeline to to set to the location of the configs directory.
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If required, you can instead download the nf-core/configs files yourself and customise the `--custom_config_base` / `params.custom_config_base` parameter in each pipeline to to set to the location of the configs directory.
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## Adding a new config
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