description:Evaluate microsattelite instability (MSI) using paired tumor-normal sequencing data
keywords:
- homoploymer,microsatellite
tools:
- msisensor:
description:MSIsensor is a C++ program to detect replication slippage variants at microsatellite regions, and differentiate them as somatic or germline.
homepage:https://github.com/ding-lab/msisensor
documentation:None
tool_dev_url:None
doi:"10.1093/bioinformatics/btt755"
licence:['MIT']
input:
- meta:
type:map
description:|
Groovy Map containing sample information
e.g. [ id:'test', single_end:false ]
- normal_bam:
type:file
description:Coordinate sorted BAM/CRAM/SAM file from normal tissue
pattern:"*.{bam,cram,sam}"
- normal_bai:
type:file
description:Index for coordinate sorted BAM/CRAM/SAM file from normal tissue
pattern:"*.{bam,cram,sam}"
- tumor_bam:
type:file
description:Coordinate sorted BAM/CRAM/SAM file from tumor tissue
pattern:"*.{bam,cram,sam}"
- tumor_bai:
type:file
description:Index for coordinate sorted BAM/CRAM/SAM file from tumor tissue
pattern:"*.{bam,cram,sam}"
- homopolymers:
type:file
description:Output file from MSIsensor scan module