Calculates the fraction of reads from cross-sample contamination based on summary tables from getpileupsummaries. Output to be used with filtermutectcalls.
keywords:
- gatk4
- calculatecontamination
- cross-samplecontamination
- getpileupsummaries
- filtermutectcalls
tools:
- gatk4:
description:|
Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools
with a primary focus on variant discovery and genotyping. Its powerful processing engine
and high-performance computing features make it capable of taking on projects of any size.
description:File containing the pileups summary table of a tumor sample to be used to calculate contamination.
pattern:"*.pileups.table"
- matched:
type:file
description:File containing the pileups summary table of a normal sample that matches with the tumor sample specified in pileup argument. This is an optional input.
pattern:"*.pileups.table"
- segmentout:
type:boolean
description:specifies whether to output the segmentation table.
output:
- contamination:
type:file
description:File containing the contamination table.
pattern:"*.contamination.table"
- segmentation:
type:file
description:optional output table containing segmentation of tumor minor allele fractions.