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name : msisensor_msi
description : Evaluate microsattelite instability (MSI) using paired tumor-normal sequencing data
keywords :
- homoploymer,microsatellite
tools :
- msisensor :
description : MSIsensor is a C++ program to detect replication slippage variants at microsatellite regions, and differentiate them as somatic or germline.
homepage : https://github.com/ding-lab/msisensor
documentation : None
tool_dev_url : None
doi : "10.1093/bioinformatics/btt755"
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licence : [ "MIT" ]
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input :
- meta :
type : map
description : |
Groovy Map containing sample information
e.g. [ id:'test', single_end:false ]
- normal_bam :
type : file
description : Coordinate sorted BAM/CRAM/SAM file from normal tissue
pattern : "*.{bam,cram,sam}"
- normal_bai :
type : file
description : Index for coordinate sorted BAM/CRAM/SAM file from normal tissue
pattern : "*.{bam,cram,sam}"
- tumor_bam :
type : file
description : Coordinate sorted BAM/CRAM/SAM file from tumor tissue
pattern : "*.{bam,cram,sam}"
- tumor_bai :
type : file
description : Index for coordinate sorted BAM/CRAM/SAM file from tumor tissue
pattern : "*.{bam,cram,sam}"
- homopolymers :
type : file
description : Output file from MSIsensor scan module
pattern : "*.msisensor_scan.tab"
output :
- meta :
type : map
description : |
Groovy Map containing sample information
e.g. [ id:'test', single_end:false ]
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- versions :
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type : file
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description : File containing software versions
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pattern : "versions.yml"
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- txt :
type : file
description : MSIsensor MSI final report file
pattern : "*.output"
- txt :
type : file
description : MSIsensor MSI DIS report file
pattern : "*.output_dis"
- txt :
type : file
description : MSIsensor MSI germline report file
pattern : "*.output_germline"
- txt :
type : file
description : MSIsensor MSI somatic report file
pattern : "*.output_somatic"
authors :
- "@kevbrick"