diff --git a/.github/CODEOWNERS b/.github/CODEOWNERS
new file mode 100644
index 00000000..b336abe3
--- /dev/null
+++ b/.github/CODEOWNERS
@@ -0,0 +1,5 @@
+# Lines starting with '#' are comments.
+# Each line is a file pattern followed by one or more owners.
+
+# **/bwa/** @drpatelh @maxulysse
+**/fastqc/**  @drpatelh @grst @ewels @FelixKrueger