name: biscuit_align description: Aligns single- or paired-end reads from bisulfite-converted libraries to a reference genome using Biscuit. keywords: - biscuit - DNA methylation - WGBS - scWGBS - bisulfite sequencing - aligner - bam tools: - biscuit: description: A utility for analyzing sodium bisulfite conversion-based DNA methylation/modification data homepage: https://huishenlab.github.io/biscuit/ documentation: https://huishenlab.github.io/biscuit/docs/alignment tool_dev_url: https://github.com/huishenlab/biscuit doi: "" licence: ["MIT"] input: - meta: type: map description: | Groovy Map containing sample information e.g. [ id:'test', single_end:false ] - reads: type: file description: | List of input fastq files of size 1 and 2 for single-end and paired-end data, respectively. - index: type: dir description: Biscuit genome index directory (generated with 'biscuit index') pattern: "BiscuitIndex" output: - meta: type: map description: | Groovy Map containing sample information e.g. [ id:'test', single_end:false ] - bam: type: file description: Output BAM file containing read alignments pattern: "*.{bam}" - versions: type: file description: File containing software versions pattern: "versions.yml" authors: - "@njspix"