name: "gatk4_leftalignandtrimvariants" description: Left align and trim variants using GATK4 LeftAlignAndTrimVariants. keywords: - normalize - norm - vcf tools: - gatk4: description: | Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capable of taking on projects of any size. homepage: https://gatk.broadinstitute.org/hc/en-us documentation: https://gatk.broadinstitute.org/hc/en-us/categories/360002369672s doi: 10.1158/1538-7445.AM2017-3590 licence: ["Apache-2.0"] input: - meta: type: map description: | Groovy Map containing sample information e.g. [ id:'test', single_end:false ] - vcf: type: file description: | The vcf file to be normalized e.g. 'file1.vcf.gz' - tbi: type: file description: | Index of the vcf file to be normalized e.g. 'file1.vcf.gz.tbi' - intervals: type: file description: Bed file with the genomic regions included in the library (optional) - fasta: type: file description: The reference fasta file pattern: "*.fasta" - fai: type: file description: Index of reference fasta file pattern: "*.fasta.fai" - dict: type: file description: GATK sequence dictionary pattern: "*.dict" output: - meta: type: map description: | Groovy Map containing sample information e.g. [ id:'test', single_end:false ] - versions: type: file description: File containing software versions pattern: "versions.yml" - vcf: type: file description: VCF normalized output file pattern: "*.{vcf.gz}" - tbi: type: file description: Tbi index for VCF file pattern: "*.tbi" authors: - "@adamrtalbot"