name: "scramble_clusteranalysis" description: The Cluster Analysis tool of Scramble analyses and interprets the soft-clipped clusters found by `cluster_identifier` keywords: - soft-clipped clusters - scramble tools: - "scramble": description: "Soft Clipped Read Alignment Mapper" homepage: "https://github.com/GeneDx/scramble" documentation: "https://github.com/GeneDx/scramble" tool_dev_url: "https://github.com/GeneDx/scramble" doi: "" licence: "['CC']" input: - meta: type: map description: | Groovy Map containing sample information e.g. [ id:'test', single_end:false ] - clusters: type: file description: Tab-delimited text file containing soft-clipped clusters. Has to be generated using scramble/clusteridentifier pattern: "*clusters.txt" - fasta: type: file description: Optional fasta reference file. This file is needed to create a VCF file and to evaluate predicted deletions. pattern: "*.{fasta,fa}" - mei_ref: type: file description: Optional fasta file containing the MEI reference. This file should only be supplied in special occasions where the default isn't correct pattern: "*.{fasta,fa}" output: - meta: type: map description: | Groovy Map containing sample information e.g. [ id:'test', single_end:false ] - versions: type: file description: File containing software versions pattern: "versions.yml" - meis_tab: type: file description: Tab-delimited text file containing MEI calls pattern: "*_MEIs.txt" - dels_tab: type: file description: Tab-delimited text file containing predicted deletions pattern: "*_PredictedDeletions.txt" - vcf: type: file description: A VCF file containing the MEI calls and/or the predicted deletions (depending on the given arguments) pattern: "*.vcf" authors: - "@nvnieuwk"