2019-09-07 11:42:06 +00:00
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@inline function anchor!(stream::BufferedStreams.BufferedInputStream, p, immobilize = true)
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stream.anchor = p
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stream.immobilized = immobilize
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return stream
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end
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@inline function upanchor!(stream::BufferedStreams.BufferedInputStream)
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@assert stream.anchor != 0 "upanchor! called with no anchor set"
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anchor = stream.anchor
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stream.anchor = 0
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stream.immobilized = false
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return anchor
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end
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function ensure_margin!(stream::BufferedStreams.BufferedInputStream)
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if stream.position * 20 > length(stream.buffer) * 19
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BufferedStreams.shiftdata!(stream)
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end
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return nothing
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end
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@inline function resize_and_copy!(dst::Vector{UInt8}, src::Vector{UInt8}, r::UnitRange{Int})
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return resize_and_copy!(dst, 1, src, r)
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end
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@inline function resize_and_copy!(dst::Vector{UInt8}, dstart::Int, src::Vector{UInt8}, r::UnitRange{Int})
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rlen = length(r)
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if length(dst) != dstart + rlen - 1
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resize!(dst, dstart + rlen - 1)
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end
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copyto!(dst, dstart, src, first(r), rlen)
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return dst
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end
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function generate_index_function(record_type, machine, init_code, actions; kwargs...)
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kwargs = Dict(kwargs)
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context = Automa.CodeGenContext(
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generator = get(kwargs, :generator, :goto),
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checkbounds = get(kwargs, :checkbounds, false),
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loopunroll = get(kwargs, :loopunroll, 0)
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)
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quote
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function index!(record::$(record_type))
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data = record.data
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p = 1
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p_end = p_eof = sizeof(data)
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initialize!(record)
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$(init_code)
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cs = $(machine.start_state)
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$(Automa.generate_exec_code(context, machine, actions))
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if cs != 0
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throw(ArgumentError(string("failed to index ", $(record_type), " ~>", repr(String(data[p:min(p+7,p_end)])))))
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end
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@assert isfilled(record)
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return record
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end
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end
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end
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function generate_readheader_function(reader_type, metainfo_type, machine, init_code, actions, finish_code=:())
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quote
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function readheader!(reader::$(reader_type))
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_readheader!(reader, reader.state)
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end
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function _readheader!(reader::$(reader_type), state::State)
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stream = state.stream
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ensure_margin!(stream)
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cs = state.cs
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linenum = state.linenum
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data = stream.buffer
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p = stream.position
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p_end = stream.available
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p_eof = -1
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finish_header = false
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record = $(metainfo_type)()
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$(init_code)
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while true
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$(Automa.generate_exec_code(Automa.CodeGenContext(generator=:table), machine, actions))
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state.cs = cs
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state.finished = cs == 0
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state.linenum = linenum
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stream.position = p
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if cs < 0
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error("$($(reader_type)) file format error on line ", linenum)
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elseif finish_header
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$(finish_code)
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break
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elseif p > p_eof ≥ 0
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error("incomplete $($(reader_type)) input on line ", linenum)
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else
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hits_eof = BufferedStreams.fillbuffer!(stream) == 0
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p = stream.position
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p_end = stream.available
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if hits_eof
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p_eof = p_end
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end
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end
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end
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end
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end
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end
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function generate_read_function(reader_type, machine, init_code, actions; kwargs...)
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kwargs = Dict(kwargs)
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context = Automa.CodeGenContext(
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generator=get(kwargs, :generator, :goto),
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checkbounds=get(kwargs, :checkbounds, false),
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loopunroll=get(kwargs, :loopunroll, 0)
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)
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quote
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function Base.read!(reader::$(reader_type), record::eltype($(reader_type)))::eltype($(reader_type))
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return _read!(reader, reader.state, record)
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end
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function _read!(reader::$(reader_type), state::State, record::eltype($(reader_type)))
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stream = state.stream
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ensure_margin!(stream)
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cs = state.cs
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linenum = state.linenum
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data = stream.buffer
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p = stream.position
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p_end = stream.available
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p_eof = -1
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found_record = false
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initialize!(record)
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$(init_code)
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if state.finished
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throw(EOFError())
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end
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while true
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$(Automa.generate_exec_code(context, machine, actions))
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state.cs = cs
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state.finished |= cs == 0
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state.linenum = linenum
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stream.position = p
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if cs < 0
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error($(reader_type), " file format error on line ", linenum, " ~>", repr(String(data[p:min(p+7,p_end)])))
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elseif found_record
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break
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elseif cs == 0
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throw(EOFError())
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elseif p > p_eof ≥ 0
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error("incomplete $($(reader_type)) input on line ", linenum)
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elseif BufferedStreams.available_bytes(stream) < 64
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hits_eof = BufferedStreams.fillbuffer!(stream) == 0
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p = stream.position
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p_end = stream.available
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if hits_eof
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p_eof = p_end
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end
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end
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end
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@assert isfilled(record)
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return record
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end
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end
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end
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# Automa.jl generated readrecord! and readmetainfo! functions
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# ========================================
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# file = header . body
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# header = metainfo*
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# body = record*
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isinteractive() && info("compiling SAM")
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const sam_metainfo_machine, sam_record_machine, sam_header_machine, sam_body_machine = (function ()
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cat = Automa.RegExp.cat
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rep = Automa.RegExp.rep
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alt = Automa.RegExp.alt
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opt = Automa.RegExp.opt
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any = Automa.RegExp.any
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metainfo = let
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tag = re"[A-Z][A-Z]" \ cat("CO")
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tag.actions[:enter] = [:mark1]
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tag.actions[:exit] = [:metainfo_tag]
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dict = let
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key = re"[A-Za-z][A-Za-z0-9]"
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key.actions[:enter] = [:mark2]
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key.actions[:exit] = [:metainfo_dict_key]
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val = re"[ -~]+"
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val.actions[:enter] = [:mark2]
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val.actions[:exit] = [:metainfo_dict_val]
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keyval = cat(key, ':', val)
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cat(keyval, rep(cat('\t', keyval)))
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end
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dict.actions[:enter] = [:mark1]
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dict.actions[:exit] = [:metainfo_val]
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co = cat("CO")
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co.actions[:enter] = [:mark1]
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co.actions[:exit] = [:metainfo_tag]
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comment = re"[^\r\n]*"
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comment.actions[:enter] = [:mark1]
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comment.actions[:exit] = [:metainfo_val]
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cat('@', alt(cat(tag, '\t', dict), cat(co, '\t', comment)))
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end
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metainfo.actions[:enter] = [:anchor]
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metainfo.actions[:exit] = [:metainfo]
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record = let
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qname = re"[!-?A-~]+"
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qname.actions[:enter] = [:mark]
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qname.actions[:exit] = [:record_qname]
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flag = re"[0-9]+"
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flag.actions[:enter] = [:mark]
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flag.actions[:exit] = [:record_flag]
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rname = re"\*|[!-()+-<>-~][!-~]*"
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rname.actions[:enter] = [:mark]
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rname.actions[:exit] = [:record_rname]
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pos = re"[0-9]+"
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pos.actions[:enter] = [:mark]
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pos.actions[:exit] = [:record_pos]
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mapq = re"[0-9]+"
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mapq.actions[:enter] = [:mark]
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mapq.actions[:exit] = [:record_mapq]
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cigar = re"\*|([0-9]+[MIDNSHPX=])+"
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cigar.actions[:enter] = [:mark]
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cigar.actions[:exit] = [:record_cigar]
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rnext = re"\*|=|[!-()+-<>-~][!-~]*"
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rnext.actions[:enter] = [:mark]
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rnext.actions[:exit] = [:record_rnext]
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pnext = re"[0-9]+"
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pnext.actions[:enter] = [:mark]
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pnext.actions[:exit] = [:record_pnext]
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tlen = re"[-+]?[0-9]+"
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tlen.actions[:enter] = [:mark]
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tlen.actions[:exit] = [:record_tlen]
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seq = re"\*|[A-Za-z=.]+"
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seq.actions[:enter] = [:mark]
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seq.actions[:exit] = [:record_seq]
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qual = re"[!-~]+"
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qual.actions[:enter] = [:mark]
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qual.actions[:exit] = [:record_qual]
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field = let
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tag = re"[A-Za-z][A-Za-z0-9]"
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val = alt(
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re"A:[!-~]",
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re"i:[-+]?[0-9]+",
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re"f:[-+]?[0-9]*\.?[0-9]+([eE][-+]?[0-9]+)?",
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re"Z:[ !-~]*",
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re"H:([0-9A-F][0-9A-F])*",
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re"B:[cCsSiIf](,[-+]?[0-9]*\.?[0-9]+([eE][-+]?[0-9]+)?)+")
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cat(tag, ':', val)
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end
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field.actions[:enter] = [:mark]
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field.actions[:exit] = [:record_field]
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cat(
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qname, '\t',
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flag, '\t',
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rname, '\t',
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pos, '\t',
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mapq, '\t',
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cigar, '\t',
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rnext, '\t',
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pnext, '\t',
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tlen, '\t',
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seq, '\t',
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qual,
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rep(cat('\t', field)))
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end
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record.actions[:enter] = [:anchor]
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record.actions[:exit] = [:record]
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newline = let
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lf = re"\n"
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lf.actions[:enter] = [:countline]
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cat(re"\r?", lf)
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end
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header′ = rep(cat(metainfo, newline))
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header′.actions[:exit] = [:header]
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header = cat(header′, opt(any() \ cat('@'))) # look ahead
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body = rep(cat(record, newline))
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return map(Automa.compile, (metainfo, record, header, body))
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end)()
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const sam_metainfo_actions = Dict(
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|
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:metainfo_tag => :(record.tag = (mark1:p-1) .- offset),
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:metainfo_val => :(record.val = (mark1:p-1) .- offset),
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:metainfo_dict_key => :(push!(record.dictkey, (mark2:p-1) .- offset)),
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:metainfo_dict_val => :(push!(record.dictval, (mark2:p-1) .- offset)),
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:metainfo => quote
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|
|
resize_and_copy!(record.data, data, offset+1:p-1)
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|
|
record.filled = (offset+1:p-1) .- offset
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|
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end,
|
|
|
|
|
:anchor => :(),
|
|
|
|
|
:mark1 => :(mark1 = p),
|
2019-09-07 23:08:12 +00:00
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|
|
:mark2 => :(mark2 = p)
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)
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|
|
generate_index_function(
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MetaInfo,
|
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|
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sam_metainfo_machine,
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|
|
:(mark1 = mark2 = offset = 0),
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|
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sam_metainfo_actions
|
|
|
|
|
) |> eval
|
|
|
|
|
|
|
|
|
|
generate_readheader_function(
|
|
|
|
|
Reader,
|
|
|
|
|
MetaInfo,
|
|
|
|
|
sam_header_machine,
|
|
|
|
|
:(mark1 = mark2 = offset = 0),
|
|
|
|
|
merge(sam_metainfo_actions, Dict(
|
|
|
|
|
:metainfo => quote
|
|
|
|
|
resize_and_copy!(record.data, data, upanchor!(stream):p-1)
|
|
|
|
|
record.filled = (offset+1:p-1) .- offset
|
|
|
|
|
@assert isfilled(record)
|
|
|
|
|
push!(reader.header.metainfo, record)
|
|
|
|
|
ensure_margin!(stream)
|
|
|
|
|
record = MetaInfo()
|
|
|
|
|
end,
|
|
|
|
|
:header => :(finish_header = true; @escape),
|
|
|
|
|
:countline => :(linenum += 1),
|
|
|
|
|
:anchor => :(anchor!(stream, p); offset = p - 1))),
|
|
|
|
|
quote
|
|
|
|
|
if !eof(stream)
|
|
|
|
|
stream.position -= 1 # cancel look-ahead
|
|
|
|
|
end
|
|
|
|
|
end
|
|
|
|
|
) |> eval
|
2019-09-07 11:42:06 +00:00
|
|
|
|
|
|
|
|
|
const sam_record_actions = Dict(
|
|
|
|
|
:record_qname => :(record.qname = (mark:p-1) .- offset),
|
|
|
|
|
:record_flag => :(record.flag = (mark:p-1) .- offset),
|
|
|
|
|
:record_rname => :(record.rname = (mark:p-1) .- offset),
|
|
|
|
|
:record_pos => :(record.pos = (mark:p-1) .- offset),
|
|
|
|
|
:record_mapq => :(record.mapq = (mark:p-1) .- offset),
|
|
|
|
|
:record_cigar => :(record.cigar = (mark:p-1) .- offset),
|
|
|
|
|
:record_rnext => :(record.rnext = (mark:p-1) .- offset),
|
|
|
|
|
:record_pnext => :(record.pnext = (mark:p-1) .- offset),
|
|
|
|
|
:record_tlen => :(record.tlen = (mark:p-1) .- offset),
|
|
|
|
|
:record_seq => :(record.seq = (mark:p-1) .- offset),
|
|
|
|
|
:record_qual => :(record.qual = (mark:p-1) .- offset),
|
|
|
|
|
:record_field => :(push!(record.fields, (mark:p-1) .- offset)),
|
|
|
|
|
:record => quote
|
|
|
|
|
resize_and_copy!(record.data, data, 1:p-1)
|
|
|
|
|
record.filled = (offset+1:p-1) .- offset
|
|
|
|
|
end,
|
|
|
|
|
:anchor => :(),
|
2019-09-07 23:08:12 +00:00
|
|
|
|
:mark => :(mark = p)
|
|
|
|
|
)
|
|
|
|
|
|
|
|
|
|
generate_index_function(
|
|
|
|
|
Record,
|
|
|
|
|
sam_record_machine,
|
|
|
|
|
:(mark = offset = 0),
|
|
|
|
|
sam_record_actions
|
|
|
|
|
) |> eval
|
|
|
|
|
|
|
|
|
|
generate_read_function(
|
|
|
|
|
Reader,
|
|
|
|
|
sam_body_machine,
|
|
|
|
|
:(mark = offset = 0),
|
|
|
|
|
merge(sam_record_actions, Dict(
|
|
|
|
|
:record => quote
|
|
|
|
|
resize_and_copy!(record.data, data, upanchor!(stream):p-1)
|
|
|
|
|
record.filled = (offset+1:p-1) .- offset
|
|
|
|
|
found_record = true
|
|
|
|
|
@escape
|
|
|
|
|
end,
|
|
|
|
|
:countline => :(linenum += 1),
|
|
|
|
|
:anchor => :(anchor!(stream, p); offset = p - 1))
|
|
|
|
|
)
|
|
|
|
|
) |> eval
|