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nf-configs/conf/pipeline/raredisease/hasta.config

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process {
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withName:'PICARD_MARKDUPLICATES' {
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memory = { check_max( 90.GB * task.attempt, 'memory' ) }
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}
withName:'DEEPVARIANT' {
cpus = { check_max( 16 * task.attempt, 'cpus' ) }
memory = { check_max( 80.GB * task.attempt, 'memory' ) }
}
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withname: BCFTOOLS_VIEW {
if (params.genome == 'GRCh37') {
ext.args = '--output-type v --apply-filters PASS --exclude "INFO/clinical_genomics_mipAF > 0.40 | INFO/swegenAF > 0.40 | INFO/clingen_ngiAF > 0.40 | INFO/gnomad_svAF > 0.40 "'
} else if (params.genome == 'GRCh38') {
ext.args = '--output-type v --apply-filters PASS --exclude "INFO/swegenAF > 0.40"'
}
publishDir = [
enabled: false,
]
}
}
params {
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sentieon_install_dir = "$SENTIEON_INSTALL_DIR/bin"
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}